Hematopoietic comparison documents seer registrars. How do i perform hematopoietic progenitor cell selection. Maintaining adequate blood cell production, as well as being able to meet increased demand, is in part under the control of a group of hormonelike glycoproteins that includes the hematopoietic growth factors and the interleukins. Early and late complications following hematopoietic stem. A total of 229 pediatric patients, who underwent hsct between 1 january 2005 and 31 december 2015 at the university children hospital wuerzburg, were studied. Choose from 301 different sets of hematopoietic agents flashcards on quizlet. Please use the ndc drug lookup to find prior authorization pa forms guiding rules of the preferred drug list pdl.
The hematopoietic and lymphoid neoplasm coding manual heme manual and the companion hematopoietic and lymphoid neoplasm database heme db are dedicated to the hard working cancer registrars across the world who meticulously identify, abstract, and code cancer data. In the case where the prior authorization pa status column indicates pa, both the brand and generic if available require pa. Stenotrophomonas maltophilia colonization during allogeneic. Failure to achieve desired therapeutic outcomes with trial on 2 or more preferred agents o documented trial period for preferred agents o documented adeadr to preferred agents appropriate diagnosis appendix a appropriate participant age o mircera. It may make it less likely that you will have severe complications or need to be hospitalized. Immunosuppressive agents antimicrobial agents fluid needs 1,500 ml x body surface area bsa 1222018 1222018 15 nutrient goals macris pc. All blood cell types arise from hematopoietic stem cells hscs that reside mainly in.
Haematopoietic stem cells hscs reside in the medulla of the bone bone marrow and have the unique ability to give rise to all of the different mature blood cell types and tissues. In addition to the material presented here, the 12th edition contains. These immature myeloblasts expand in the bone marrow, peripheral blood, and other tissues, with a corresponding reduction in the production. Issues cost treatment are raised by these agents, but the true clin ical value of hematopoietic growth factors needs to be studied more rigorously, with emphasis on quality of life. Oct 16, 2018 a total of 229 pediatric patients, who underwent hsct between 1 january 2005 and 31 december 2015 at the university children hospital wuerzburg, were studied. Original article reduced intensity melphalan conditioning. Hematopoietic stem and progenitor cells stemcell technologies. Hematopoietic agents this chapter will be most useful after having a basic understanding of the material in chapter 37, hematopoietic agents. The clinical program shall have a written safety manual that includes.
The cells undergo sequential divisions as they mature and the mature cells have limited life spans. For dosing instructions of combination agents administered with adcetris, see. Hematopoietic agents free download as powerpoint presentation. Aetna is the brand name used for products and services provided by one or more of the aetna group of subsidiary companies, including aetna life insurance company and its affiliates aetna. Hematopoietic agents workbook and casebook for goodman. If you have any questions, please submit a question to seer and choose hematopoietic rules as the subject. Hematopoietic comparisons for manual and database 2010, 2012, 2014 pdf, 742 kb note. University of michigan hematopoietic agents epogen or procrit epoetin alfa, aranesp darbepoetin some of the information needed to make a determination for coverage is not specifically requested on the michigan prior authorization request form. Preparative conditioning for allogeneic hematopoietic sct.
Traditional and advanced cell cultures in hematopoietic. Agerelated hematopoietic changes occur gradually over time, but can potentially be reversed. Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytesthey are used in the treatment of anemias. Many of the changes observed in the hematopoietic system with age are due to alterations in hscs and committed progenitors. Safety considerations in phase 1 trials joseph toerner, md, mph deputy director for safety. The conventional practice of allogeneic hsct involves administration of myelotoxic agents e. Shelanski, md,phd professor of pathology and cell biology. Casematched comparison with standard versus reduced intensity conditioning regimen in chronic myeloid leukemia patients. The factjacie international standards for hematopoietic cellular therapy. Achieve and maintain hemoglobin levels within the range of 10 to 12 gdl in the following conditions. Hematology hematopoietic agents for the treatment of anemias. All cellular blood components are derived from haematopoietic stem cells. The aging hematopoietic system undergoes many changes. Pertaining to hematopoiesis, the production of all types of blood cells.
The implementation of hematopoietic progenitor cell hpc selection is employed by some stem cell processing facilities to mitigate this complication. Medical nutrition therapy in hematopoietic cell transplantation. We collect clinical information before elective inpatient admissions andor selected ambulatory procedures and services take place. Prior authorization list general information rightcare authorization requirement list effective january 1, 2020 3 1. Hematology hematopoietic agents for the treatment of. The process is regulated in part by hematopoietic growth factorsnaturally occurring hormones that stimulate the proliferation and differentiation of hematopoietic stem cells, and enhance function in the mature forms of those cells. Irradiation is repeated 3 hrs later for a total dose of 700r 1200r split dose irradiation is used to limit the nonhematopoietic toxicity usually intestinal damage. Jul 19, 2018 materials, study design and definitions. Ohio medicaid unified pdl effective january 1, 2020 page 1 ohio medicaid pharmacy benefit management program unified preferred drug list medicaid feeforservice and managed care plans. Preventing infection is an important part of cancer treatment.
Hematopoietic definition of hematopoietic by medical dictionary. All relevant data are within the paper and its supporting information files. Hematopoiesis is the process by which our bodies make red blood cells, white blood cells, and platelets. Request pdf hematopoietic agents hematopoesis is a lifelong process that involves the continuous formation and turnover of blood cells. Hematopoietic stimulants help your body make new white blood cells and help prevent infection after chemotherapy. For the most part, this process occurs in the marrow cavities of the skull, vertebral bodies. Hematopoietic stem cells hscs represent one of the first recognized somatic stem cell types. Typically, the generic is preferred when available unless the brandname drug appears on the masshealth brand name preferred over generic drug list. As such, nearly 200 genes have been examined for roles in hsc function in knockout mice.
The conventional classical practice of allogeneic hct involves administration of cytotoxic agents e. Hematopoietic stem cell transplantation hsct is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. The regulation of blood cell production is complex. Hematopoietic stem cell transplantation hsct overview. Current uses and outcomes of hematopoietic stem cell transplantation. Hematopoietic stem cells are rare bone marrow cells that manifest selfrenewal and lineage commitment, resulting in cells destined to differentiate into the 9 distinct bloodcell lineages. Ohio medicaid pdl effective january 1, 2020 page 6 analgesic agents. Howitreatpatientswhomobilizehematopoieticstemcellspoorly.
During hematopoiesis, a small fraction of cells undergo cell death. Hematopoietichematinic agents hematopoietics and hematinics also known as erythropoiesis stimulating agents esas are a covered nevada medicaid benefit for recipients who meet the following criteria. The finite life span of most mature blood cells requires their continuous replacement, a process termed hematopoiesis. However, asct is the standard of care in first line therapy for transplant eligible patients in the era of novel drugs.
Hematopoesis is a lifelong process that involves the continuous formation and turnover of blood cells. Stenotrophomonas maltophilia colonization during allogeneic hematopoietic stem cell transplantation is associated. Hematopoietic agents workbook and casebook for goodman and. We revisited the medical records of 264 patients with a diagnosis of aml, who underwent a first allohsct at our institution between january 2006 and march 2016 and extended the cohort to december 2016 up to overall 291 patients. University of michigan hematopoietic agents epogen or procrit epoetin alfa, aranesp darbepoetin some of the information needed to make a determination for coverage is not specifically requested on the michigan prior authorization request form for prescription drugs. A model of hematopoietic bone marrow apoptosis during growth. Irradiation is repeated 3 hrs later for a total dose of 700r 1200r split dose irradiation is used to limit the non hematopoietic toxicity usually intestinal damage. Hematopoietic definition of hematopoietic by medical. Hematopoietic cell transplantation hct refers to a procedure in which hematopoietic stem cells. The beneficial treatment effect in this procedure is due to a combination of initial eradication of malignant. Hematology hematopoietic agents for the treatment of anemias hematopoietic agent common uses what i need to know as a brand new nurse ferrous sulfate. Reducedintensity conditioning ric refers to chemotherapy regimens that. Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes.